Contact Information:

 Department of Chemistry

 Office: CIS E305

 Email:  r-ismagilov@uchicago.edu

 Voice: 773 702 5816

 Fax:    773 834 3544

 Mailing Address: 929 East 57th Street,

 Chicago, IL 60637 Directions

POSTDOCTORAL:

    We welcome outstanding postdoctoral applications from talented, motivated individuals.  Below are several examples of potential projects for postdocs.  For additional ongoing projects see the list of publications.

Respond with a CV and a brief statement describing your expertise and interests to ismagilovlab@uchicago.edu.

Complexity in general

     A postdoctoral position is available to use microfluidics and chemistry to determine the underlying mechanisms by which complex biological networks operate (results for the blood clotting network were reported in Angew Chemie 2004 43:1531, and PNAS 2006 103: 15747, and for Drosophila in Nature 2005 434: 1134).  The ideal candidate would be highly motivated, have a strong publication record, and have prior expertise in micro/nanotechnology, chemical biology, or complex systems biology. 

Crystallization and structural analysis of proteins in microcapillaries

    This project aims to develop technologies for crystallization and structural analysis of proteins in nanoliter volumes. The work will be carried out in collaboration with groups of other members (Lance Stewart, deCODE biostructures, Ray Stevens and Peter Kuhn, Scripps) of the ATCG3D center (http://www.atcg3d.org/). Experience in expression, purification, crystallization, and structural analysis of macromolecules is essential. Strong leadership skills, communication skills, and interest in technology development are highly desirable.

Microfluidic crystallization of membrane proteins

    This project aims to develop microfluidic technologies to enable crystallization of membrane proteins in nanoliter volumes inside microcapillaries. The work will require interactions with the ATCG3D center (http://www.atcg3d.org/ -- Lance Stewart, deCODE biostructures, PI) and JCIMPT center (http://jcimpt.scripps.edu/ -- Ray Stevens and Peter Kuhn), and solid communication skills will be important for candidates. Experience in expression, purification, crystallization, and structural analysis of membrane proteins is highly desirable. Candidates with strong interest in interdisciplinary research and in technology development will be preferred. Experience in microfluidics is not required.

Study robustness of development in Drosophila using microfluidics

    NIH-funded postdoctoral position is available to use microfluidics to determine the mechanism that maintains robustness of early patterning of the Drosophila embryo (initial results reported in Nature 2005 434: 1134-1138).  Expertise in Drosophila developmental biology is required. The ideal candidate would be highly motivated, interdisciplinary, and seeking to learn microfluidic technology.

Use C.elegans and  microfluidics to understand complex networks

    A postdoctoral position is available, in collaboration with the Morimoto lab, to use C. elegans and microfluidics to study protein aggregation. Expertise in C. elegans biology is required and experience creating transgenic animals is desirable. The ideal candidate would be highly motivated, interdisciplinary, and seeking to learn microfluidic technology.

UNDERGRADUATE STUDENTS:

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